2021

​

RAY: CRISPR diagnostic for rapid and accurate detection of SARS-CoV2 variants on a paper strip. Manoj Kumar, Sneha Gulati, Asgar Hussain Ansari, Rhythm Phutela, Sundaram Acharya, Poorti Kathpalia, Akshay Kanakan, Ranjeet Maurya, Janani Srinivasa Vasudevan, Aparna Murali, Rajesh Pandey, Souvik Maiti, Debojyoti Chakraborty. MedRxiv (2021). https://doi.org/10.1101/2021.02.01.21250900

 

Rapid and accurate nucleobase detection using FnCas9 and its application in COVID-19 diagnosis. Mohd Azhar, Rhythm Phutela, Manoj Kumar, Asgar Hussain Ansari, Riya Rauthan, Sneha Gulati, Namrata Sharma, Dipanjali Sinha, Saumya Sharma, Sunaina Singh, Sundaram Acharya, Sajal Sarkar, Deepanjan Paul, Poorti Kathpalia, Meghali Aich, Paras Sehgal, Gyan Ranjan, Rahul C Bhoyar, Genetic Epidemiology IndiCovGEN Consortium, Khushboo Singhal, Harsha Lad, Pradeep Kumar Patra, Govind Makharia, Giriraj Ratan Chandak, Bala Pesala, Debojyoti Chakraborty, Souvik Maiti. Biosensors and Bioelectronics (2021). https://doi.org/10.1016/j.bios.2021.113207

 

CRISPR Cas9 based genome editing in inherited retinal dystrophies. Mayank Bansal, Sundaram Acharya, Saumya Sharma, Rhythm Phutela, Riya Rauthan, Souvik Maiti, Debojyoti Chakraborty. Ophthalmic Genetics (2021).  https://doi.org/10.1080/13816810.2021.1904421

​

Low-cost CRISPR diagnostics for resource-limited settings. Sneha Gulati, Souvik Maiti, Debojyoti Chakraborty. Trends in Genetics (2021). https://doi.org/10.1016/j.tig.2021.05.001

​

Voices of biotech research. Annabi N, Baker M, Boettiger A, Chakraborty D, Chen Y, Corbett KS, Correia B, Dahlman J, de Oliveira T, Ertuerk A, Yanik MF, Henaff E, Huch M, Iliev ID, Jacobs T, Junca H, Keung A, Kolodkin-Gal I, Krishnaswamy S, Lancaster M, Macosko E, Martínez-Núñez MA, Miura K, Molloy J, Cruz AO, Platt RJ, Posey AD Jr, Shao H, Simunovic M, Slavov N, Takebe T, Vandenberghe LH, Varshney RK, Wang J. Nature Biotechnology (2021). https://doi.org/10.1038/s41587-021-00847-1 

​

​Rapid identification and tracking of SARS-CoV-2 variants of concern. Debojyoti Chakraborty, Anurag Agrawal, Souvik Maiti. The Lancet (2021). https://doi.org/10.1016/S0140-6736(21)00470-0

​

2020

​

Ophthalmic genetics practice and research in India: Vision in 2020. Mayank Bansal, Radhika Tandon, Rohit Saxena, Arundhati Sharma, Sagnik Sen, Alisha Kishore, Pradeep Venkatesh, Souvik Maiti, Debojyoti Chakraborty. American Journal of Medical Genetics. Partc C, seminars in Medical Genetics (2020). https://doi.org/10.1002/ajmg.c.31827

Terminal uridylyl transferase-mediated site-directed access to clickable chromatin employing CRISPR-dCas9. Jerrin Thomas George, Mohd. Azhar, Meghali Aich, Dipanjali Sinha, Uddhav B Ambi, Souvik Maiti, Debojyoti Chakraborty, and Seergazhi G Srivatsan. Journal of the American Chemical Society (2020). https://doi.org/10.1021/jacs.0c06541

​

Role of lncRNAs in stem cell maintenance and differentiation. Meghali Aich, Debojytoi Chakraborty. (2020). Current Topics in Developmental Biology (2020). https://doi.org/10.1016/bs.ctdb.2019.11.003

​

The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells. Li Ding, Maciej Paszkowski-Rogacz, Jovan Mircetic, Debojyoti Chakraborty, Frank Buchholz. Life Science Alliance (2020). https://doi.org/10.26508/lsa.202000792

 

2019

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing. Sundaram Acharya*, Arpit Mishra*, Deepanjan Paul*, Asgar Hussain Ansari, Mohd. Azhar, Manoj Kumar, Riya Rauthan, Namrata Sharma, Meghali Aich, Dipanjali Sinha, Saumya Sharma, Shivani Jain, Arjun Ray, Suman Jain, Sivaprakash Ramalingam, Souvik Maiti, and Debojyoti Chakraborty. Proceedings of the National Academy of Sciences (2019). https://doi.org/10.1073/pnas.1818461116

 

2018

Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma. Subhashree Nayak, Meghali Aich, Anupam Kumar, Suman Sengupta, Prajakta Bajad, Parashar Dhapola, Deepanjan Paul, Kiran Narta, Suvendu Purkrait, Bharati Mehani, Ashish Suri, Debojyoti Chakraborty, Arijit Mukhopadhyay, Chitra Sarkar. Scientific Reports (2018). https://doi.org/10.1038/s41598-018-26000-8

 
A G-quadruplex motif at the 3’ end of sgRNAs improves CRISPR-Cas9-based genome editing efficiency. Smita Nahar, Paras Sehgal, Mohd. Azhar, Manish Rai, Amrita Singh, Sridhar Sivasubbu, Debojyoti Chakraborty, and Souvik Maiti. Chemical Communications (2018). 

https://doi.org/10.1039/C7CC08893K

2017

LncRNA Panct1 maintains mouse embryonic stem cell identity by recruiting TOBF1 to Oct-Sox sequences in early G1. Debojyoti Chakraborty, Maciej Paszkowski-Rogacz, Nicolas Berger, Li Ding, Jovan Mircetic, Jun Fu, Vytautas Iesmantavicius, Chunaram Choudhary, Konstantinos Anastassiadis, A Francis Stewart, Frank Buchholz. Cell Reports (2017).

https://doi.org/10.1016/j.celrep.2017.11.045

​

CRISPR-Cas9: a new tool for gene therapy. Saumya Sharma, Souvik Maiti, Debojyoti Chakraborty. eLS (2017). 

https://doi.org/10.1002/9780470015902.a0026629

2016

CRISPR/Cas9: a historical and chemical biology perspective of targeted genome engineering. Amrita Singh, Debojyoti Chakraborty, and Souvik Maiti. Chemical Society Reviews (2016). https://doi.org/10.1039/C6CS00197A

​

Inactivation of cancer mutations utilizing CRISPR/Cas9. Christina Gebler, Tim Lohoff, Maciej Paszkowski-Rogacz, Jovan Mircetic, Debojyoti Chakraborty, Aylin Camgoz, Martin V Hamann, Mirko Theis, Christian Thiede, Frank Buchholz. Journal of the National Cancer Institute (2016). https://doi.org/10.1093/jnci/djw183

Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Janet Karpinski, Ilona Hauber, Jan Chemnitz, Carola Schäfer, Maciej Paszkowski-Rogacz, Debojyoti Chakraborty, Niklas Beschorner, Helga Hofmann-Sieber, Ulrike C Lange, Adam Grundhoff, Karl Hackmann, Evelin Schrock, Josephine Abi-Ghanem, M Teresa Pisabarro, Vineeth Surendranath, Axel Schambach, Christoph Lindner, Jan van Lunzen, Joachim Hauber, and Frank Buchholz. Nature Biotechnology (2016).

https://doi.org/10.1038/nbt.3467​

2015

Targeting Human Long-Noncoding Transcripts by Endoribonuclease-prepared siRNAs. Mirko Theis, Maciej Paszkowski-Rogacz, Ina Weisswange, Debojyoti Chakraborty, Frank Buchholz. Journal of Biomolecular Screening (2015).

https://doi.org/10.1177/1087057115583448

​

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells. Li Ding, Maciej Paszkowski-Rogacz, Maria Winzi, Debojyoti Chakraborty, Mirko Theis, Sukhdeep SinghGiovanni Ciotta, Ina Poser, Assen Roguev, Wai Kit Chu, Chunaram Choudhary, Matthias Mann, A. Francis Stewart, Nevan Krogan, Frank Buchholz. Cell Systems (2015).

https://doi.org/10.1016/j.cels.2015.08.002

​

Before 2015

Universal Tre (uTre) recombinase specifically targets the majority of HIV-1 isolates. Janet Karpinski, Jan Chemnitz, Ilona Hauber Josephine Abi-Ghanem, Maciej Paszkowski-Rogacz, Vineeth Surendranath, Debojyoti Chakraborty,  Niklas Beschorner, Helga Hofmann-Sieber, Ulrike C Lange, Adam Grundhoff, Karl Hackmann, Evelin Schrock, Josephine Abi-Ghanem, M Teresa Pisabarro, Vineeth Surendranath, Axel Schambach, Christoph Lindner, Jan van Lunzen, Joachim Hauber, Frank Buchholz. Journal of the International AIDS Society (2014). https://doi.org/10.7448/IAS.17.4.19706

Combined RNAi and localization for functionally dissecting long noncoding RNAs. Debojyoti Chakraborty, Dennis Kappei, Mirko Theis, Anja Nitzsche, Li Ding, Maciej Paszkowski-Rogacz et al. Nature Methods (2012). https://doi.org/10.1038/nmeth.1894